This gene encodes a member of the GRB2/Sem5 ( C. elegans homolog)/Drk ( Drosophila homolog) family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR- ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain.
Usage examples of "grap".
I stick my head aroun the partition an Sue has managed to grap a holt of Major Fritch an he has got his han down in her space suit.
Ole Wanda is standin there with her snout pokin out of the boxcar, an I runned up beside her an grapped her by the ear an pulled her down.
Next, I runned up to where Dan was settin, right behin her in the boxcar door, an grapped him by the shoulders an set him down easy as I could.
Somebody says that is because when they is out in the desert an gotta take a shit, they can grap ahold of the ends of the shoes when they bend over an it keeps them on balance.