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GLC may refer to:

  • GLC (rapper), an American rapper signed to Kanye West's G.O.O.D. Music record label
  • "GLC: The Carnage Continues...", an episode of The Comic Strip Presents...
  • Mazda Familia, also known as the Mazda GLC (Great Little Car), a car sold in North America 1977–1985
  • Mercedes-Benz GLC-Class
  • Gas-liquid chromatography, a type of chromatography
  • Geographic Locator Codes
  • George Costanza, a fictional character on the television series Seinfeld
  • Glasgow Central railway station, a railway station in Glasgow, Scotland
  • International Linear Collider, or Global Linear Collider
  • Glucose (Glc)
  • God's Learning Channel
  • Goldie Lookin Chain, Welsh rappers
  • Government-linked company (or corporation)
  • Government Law College, Mumbai
  • Great Lakes Central Railroad
  • Greater London Council
  • Green Lake Crew, a rowing club based in Seattle, Washington
GLC (rapper)

Leonard D. Harris, better known by his stage name GLC, is an American rapper from Chicago.