What is "gabaculine"

n. A naturally occurring neurotoxin, first isolated from ''Streptomyces toyacaensis'' bacteria, which acts as a potent and irreversible GABA transaminase inhibitor and GABA reuptake inhibitor.

Gabaculine is a naturally occurring neurotoxin first isolated from the bacteria Streptomyces toyacaensis, which acts as a potent and irreversible GABA transaminase inhibitor, and also a GABA reuptake inhibitor. Gabaculine is also known as 3-amino-2,3-dihydrobenzoic acid hydrochloride and 5-amino cyclohexa-1,3 dienyl carboxylic acid. Gabaculine increased GABA levels in the brain and had an effect on convulsivity in mice.