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Eoxins are a family of proinflammatory eicosanoids (signaling compounds that regulate inflammatory and immune responses) that are produced in human eosinophils (a class of white blood cells) and mast cells through the metabolism of arachidonic acid, an omega-6 (ω-6) fatty acid, by the arachidonate 15-lipoxygenase-1 enzyme. The eoxins represent 14,15- leukotriene analogs and are synthesized in a similar manner to the standard leukotrienes. Eoxins contribute to inflammation in airway allergies and certain types of cancers, particularly Hodgkin's lymphoma (a cancer originating from white blood cells), prostate cancer, and colon carcinoma.