Wiktionary
drapetomania
n. (context dated English) an overwhelming urge to run away (from home, a bad situation, responsibility, etc.)
Wikipedia
Drapetomania
Drapetomania was a conjectural mental illness that, in 1851, American physician Samuel A. Cartwright hypothesized to cause Black slaves to flee captivity. It has since been debunked as pseudoscience and part of the edifice of scientific racism.
Usage examples of "drapetomania".
He also concluded that the slave's chronic tendency to run away was in reality the symptom of yet another African disease, Drapetomania, which he believed would eventually be medically cured.