What is "domperidone"

n. (context pharmaceutical drug English) An antidopaminergic drug used to suppress nausea and vomiting.

Domperidone ( INN, USAN, BAN, JAN) (brand names Motilium, Motillium, Motinorm Costi, Nomit, Brulium, Molax) is a drug developed by Janssen Pharmaceutica that acts as a peripherally selective antagonist of the dopamine D and D receptors. It is administered orally, rectally, or intravenously. Domperidone is used to relieve nausea and vomiting; to increase the transit of food through the stomach (that is, as a prokinetic agent via increasing gastrointestinal peristalsis); and to promote lactation ( breast milk production) by release of prolactin. It is also used in scientific research to study the biological function of dopamine, an important neurotransmitter and hormone, in the body.

Domperidone is available in the form of tablets, orally disintegrating tablets (based on Zydis technology), suspension and suppositories.