What is "desmoteplase"

n. A chemical found in the saliva of vampire bats that catalyzes the conversion of plasminogen to plasmin, used as a thrombolytic.

Desmoteplase is a novel, highly fibrin-specific thrombolytic agent in phase III of clinical development. In 2009, two large trials (DIAS-3 and DIAS-4) were started, and the results of these studies will determine whether desmoteplase will gain marketing authorization as a safe and effective treatment for patients with acute ischaemic stroke. Filing with health authorities is estimated in the second quarter of 2014. The Danish pharmaceutical company, Lundbeck, owns the worldwide rights to desmoteplase.