Wiktionary
desmethyl
a. (context organic chemistry in combination English) Used to name organic compounds from which a methyl group has been removed
Wikipedia
Desmethyl
Desmethyl is a term used in organic chemistry to refer to a methyl group that has been removed. It is often substituted in nomenclature for the more general Nor- prefix, the removal of one carbon atom along with the accompanying hydrogen atoms, however this prefix can be used to refer to two other structure changes.
Examples include desmethyltramadol and desmethylsertraline.