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Culham is a village and civil parish in a bend of the River Thames, south of Abingdon in Oxfordshire.

The parish includes Culham Science Centre and the European School, Culham. The parish is bounded by the Thames to the north, west and south, and by present and former field boundaries to the east. It is low-lying and fairly flat, rising from the Thames floodplain in the south to a north-facing escarpment in the north up to above sea level.

The 2011 Census recorded its population as 453.