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CMF

CMF, a three letter acronym, may stand for:

CMF (chemotherapy)

Cyclophosphamide Methotrexate Fluorouracil (CMF) is a commonly used regimen of breast cancer chemotherapy that combines three anti-cancer agents: cyclophosphamide, methotrexate, and 5-fluorouracil (5-FU).

While it is no longer considered most efficient all-around chemotherapy it retains a great importance in the treatment of elderly patients with luminal cancers and may become important for the treatment of estrogen receptor negative androgen receptor positive luminal ( GATA3 expressing) breast cancer.

The regimen was designed in order to mimic the highly successful regimen developed to treat Hodgkin's lymphoma.