Wikipedia
Chondroprotection
A chondroprotective compound is a specific compound or chemical that delays progressive joint space narrowing characteristic of arthritis and improves the biomechanics of articular joints by protecting chondrocytes. These agents perform various functions, such as:
- Stimulating chondrocyte synthesis of collagen and proteoglycans
- Enhancing synoviocyte production of hyaluronan
- Inhibiting cartilage degradation
- Preventing fibrin formation in the vasculature
Chondroprotective agents can include both endogenous and synthetic chemicals. Endogenous molecules include hyaluronic acid, glucosamine, and chondroitin sulfate.