Find the word definition


n. (context biochemistry English) Any of several peptide hormones that stimulate the digestion of fat and protein; abbreviated to CCK.


Cholecystokinin (CCK or CCK-PZ; from Greekchole, "bile"; cysto, "sac"; kinin, "move"; hence, move the bile-sac ( gallbladder)) is a peptide hormone of the gastrointestinal system responsible for stimulating the digestion of fat and protein. Cholecystokinin, previously called pancreozymin, is synthesized and secreted by enteroendocrine cells in the duodenum, the first segment of the small intestine, and causes the release of digestive enzymes and bile from the pancreas and gallbladder, respectively. It also acts as a hunger suppressant. Recent evidence has suggested that it also plays a major role in inducing drug tolerance to opioids like morphine and heroin, and is partly implicated in experiences of pain hypersensitivity during opioid withdrawal.

Usage examples of "cholecystokinin".

Amy also learned how to pronounce cholecystokinin, for the same reason that Cletus learned how to play the violin.

A fatty meal will stimulate the production of unusually high quantities of cholecystokinin, which will stimulate the gallbladder strongly, which will squirt a greater-than-usual supply of bile salt (the emulsifying ingredient) into the intestine, which will emulsify the fat that started the whole procedure and bring about its digestion.