Buto (, , Butu), Butus (, Boutos), or Butosus, now Tell al-Fara'in ("Pharaohs' Mound") and the village of Ibtu or Abtu near the city of Desouk , was an ancient city located 95 km east of Alexandria in the Nile Delta of Egypt. The city stood on the Sebennytic arm of the Nile, near its mouth, and on the southern shore of the Butic Lake (, Boutikē limnē). It is the modern Kem Kasir.
Buto originally was two cities, Pe and Dep, which merged into one city that the Egyptians named Per- Wadjet. The goddess Wadjet was its local deity, often represented as a cobra, also considered the patron deity of Lower Egypt. Her oracle was located in her renowned temple in that city. An annual festival held in the city celebrated Wadjet. The city also contained a sanctuary of Horus and much later, became associated with Isis.
The city was an important site in the Predynastic era of Ancient Egypt that includes the cultural developments of ten thousand years from the Paleolithic to 3100 BC. Archaeological evidence shows that Upper Egyptian culture replaced the Buto-culture at the delta when Upper and Lower Egypt were unified, and the replacement is considered important evidence for the unification of the two portions of Egypt into one entity. At that time Wadjet joined Nekhbet, who was represented as a white vulture and held the same position as the patron of Upper Egypt, and together they were known as the two ladies  who were the patrons of the unified Egypt. The image of Nekhbet joined Wadjet on the Uraeus that would encircle the crown of the pharaohs who ruled the unified Egypt.
The Greeks coined the toponym Buto under the Ptolemaic Kingdom a dynasty that ruled from 305 to 30 BC. It served as the capital, or according to Herodian, merely the principal village of the Nile Delta. Herodotus (l. c.) styled it the Chemmite nome, Ptolemy knew it as the Phthenothite nome (, iv. 5. § 48), and Pliny the Elder as Ptenetha.
The Greek historians record that the town was celebrated for its monolithite temple and oracle of the goddess Wadjet (Buto), whom the Greeks identified with Leto or Latona. A yearly feast was held there in honour of the goddess.
They noted that at Buto there was also a sanctuary of Horus (associated by the ancient Greeks with Apollo) and of Bastet (associated with Artemis).
The Greek name, Buto, is nearly allied to that of Muth or Maut, their appellations for Isis, as Mother of the World.
According to these same late sources, the shrew was worshipped at Buto.
Buto may refer to:
- Buto, an Ancient Egyptian city
- Buto, another name for the Egyptian goddess Wadjet
- Butoh, a modern Japanese form of dance
The Diocese of Buto is a suppressed, vacant and titular see of both the Roman Catholic and Coptic Churches, centered on the ancient City of Buto in the Nile Delta of Egypt.