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biotransformation

n. (context biochemistry English) The changes (both chemical and physical) that occur to a substance (especially a drug) by the actions of enzymes within an organism

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Biotransformation

Biotransformation is the chemical modification (or modifications) made by an organism on a chemical compound. If this modification ends in mineral compounds like CO, NH, or HO, the biotransformation is called mineralisation.

Biotransformation means chemical alteration of chemicals such as nutrients, amino acids, toxins, and drugs in the body. It is also needed to render non polar compounds polar so that they are not reabsorbed in renal tubules and are excreted. Biotransformation of xenobiotics can dominate toxicokinetics and the metabolites may reach higher concentrations in organisms than their parent compounds.