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Longman Dictionary of Contemporary English
barbiturate
noun
EXAMPLES FROM CORPUS
▪ Also, an overdose of barbiturates can severely depress the central nervous system and lead to death.
▪ Certain mixtures of drugs can be deadly, for example, alcohol plus barbiturates.
▪ Drugs such as anticoagulants, antacids, barbiturates, alcohol and tobacco may increase the likelihood of the condition developing.
▪ However, anyone tolerant to barbiturates, alcohol, and other general central nervous system depressants show some cross-tolerance to benzodiazepines.
▪ Once the first line of treatment for insomnia, barbiturates have now been almost completely abandoned for this use.
▪ She died at age 44, with barbiturates in her blood and a plastic bag over her head.
▪ The cause of death was given as a combined overdose of barbiturates and alcohol.
▪ This finding is consistent with other reports showing that restitution of the damaged mucosa takes place in barbiturate anaesthetised rats.
Douglas Harper's Etymology Dictionary
barbiturate

1928 (morphine barbiturate is from 1918), from German, coined 1863 by chemist Adolf von Baeyer (1835-1917) from Barbitursäure "barbituric acid," itself coined by Baeyer, perhaps from woman's name Barbara, or perhaps from Latin barbata, in Medieval Latin usnea barbata, literally "bearded moss." Second element is because it was obtained from uric acid. With chemical ending -ate (3).

Wiktionary
barbiturate

n. 1 (context organic compound English) Any salt or ester of barbituric acid. 2 (context pharmacology English) Any of derivatives of barbituric acid that act as depressants of the central nervous system and are used as sedatives or hypnotics.

WordNet
barbiturate

n. organic compound having powerful soporific effect; overdose can be fatal

Wikipedia
Barbiturate

Barbiturates are drugs that act as central nervous system depressants, and can therefore produce a wide spectrum of effects, from mild sedation to total anesthesia. They are also effective as anxiolytics, hypnotics, and anticonvulsants. Barbiturates also have analgesic effects; however, these effects are somewhat weak, preventing barbiturates from being used in surgery in the presence of other analgesics ( opioids or volatile anesthetics such as halothane).

Barbiturates have addiction potential, both physical and psychological. They have largely been replaced by benzodiazepines in routine medical practice - particularly in the treatment of anxiety and insomnia, due to the significant decrease in risk of overdose and the lack of an antidote for barbiturate overdose. Despite this, barbiturates are still in use for various purposes: in general anesthesia, epilepsy, treatment of acute migraines or cluster headaches, euthanasia, capital punishment, and assisted suicide. Barbiturates are derivatives of barbituric acid.

Usage examples of "barbiturate".

And a barbiturate, something called zolpidem, which is a sleeping pill also known by the brand name Ambien.

In an emergency they could exchange the tranquilizer for a powerful barbiturate that allowed them to escape many of the horrors of their captivity.

Nembutal: Nembutal is a short-acting barbiturate with sedative and hypnotic effects.

Seconal is probably the most popular blackmarket barbiturate, as it is very popular with doctors.

Although the whole notion of the use of deep barbiturate sedation as a treatment had been dismissed as dangerous and ineffective by its pioneer Dr William Sargant in the fifties, Ambrose Goddard was convinced it could repair broken minds.

German boy took the case itself and all the saleable items like barbiturates, and gave Misha the rubbish.

At midnight, devastated by exhaustion and rage, Maruja took two of the powerful barbiturates and did not wake up until eight the next morning.

Barbiturates Barbiturates are basically the opposite of amphetamines: that is, they act to depress the central nervous system.

The sleep induced by barbiturates is not normal sleep, in the sense that it seriously cuts down on the normal dream activity.

This, as with barbiturates, is extremely dangerous when taken, if the user is infected or impaired.

Mixing barbiturates and amphetamines usually results in an insane, unpleasant experience, although there are some freaks who swear by it.

Thus the training routine amounts to amphetamines in the morning, steroids in the day, and barbiturates at night.

A time is reached, during the administration of barbiturates, when so much of a drug is needed to bring about artificial sleep that the side-effects are likely to cause death.

We have heard his toxicology report, his findings of alcohol and barbiturates in the bloodstream.

It is quite conceivable to me that the decedent swallowed barbiturates at this most dreadful moment in time, either in a misguided attempt to ease her mental anguish, or perhaps to numb her senses before walking into that lake.