Crossword clues for azole
The Collaborative International Dictionary
Azole \Az"ole\, n. [From Azote.] (Org. Chem.) Any of a large class of compounds characterized by a five-membered ring which contains an atom of nitrogen and at least one other noncarbon atom (nitrogen, oxygen, sulphur). The prefixes furo-, thio, and pyrro- are used to distinguish three subclasses of azoles, which may be regarded as derived respectively from furfuran, thiophene, and pyrrol by replacement of the CH group by nitrogen; as, furo-monazole. Names exactly analogous to those for the azines are also used; as, oxazole, diazole, etc.
n. (context organic compound English) Any of a class of five-membered unsaturated heterocycles having three carbon atoms, one nitrogen atom and two double bonds
Azoles are a class of five-membered heterocyclic compounds containing a nitrogen atom and at least one other non-carbon atom (i.e. nitrogen, sulfur, or oxygen) as part of the ring. Their names originate from the Hantzsch–Widman nomenclature. The parent compounds are aromatic and have two double bonds; there are successively reduced analogs (azolines and azolidines) with fewer. One, and only one, lone pair of electrons from each heteroatom in the ring is part of the aromatic bonding in an azole. Names of azoles maintain the prefix upon reduction (e.g., pyrazoline, pyrazolidine). The numbering of ring atoms in azoles starts with the heteroatom that is not part of a double bond, and then proceeds towards the other heteroatom.