Find the word definition

Wiktionary
argonaute

n. (context protein genetics English) Any of a group of proteins responsible for the gene silencing phenomenon known as RNA interference

Wikipedia
Argonaute

The Argonaute protein family plays a central role in RNA silencing processes, as essential catalytic components of the RNA-induced silencing complex (RISC). RISC is responsible for the gene silencing phenomenon known as RNA interference (RNAi). Argonaute proteins bind different classes of small non-coding RNAs, including microRNAs (miRNAs), small interfering RNAs (siRNAs) and Piwi-interacting RNAs (piRNAs). Small RNAs guide Argonaute proteins to their specific targets through sequence complementarity (base pairing), which then leads to mRNA cleavage or translation inhibition.

Lentiviral delivery of designed shRNA's and the mechanism of RNA interference in mammalian cells.

Usage examples of "argonaute".

The boat had been transferred from their last ship Argonaute, the Frog prize, but Bolitho had said that he would leave it to his coxswain to recruit a new crew from Hyperion.

Allday had said nothing about him since the young sailor had left Argonaute on their return to England.

He had been performing the duties of second-coxswain in the prize Argonaute to help Allday, who was too proud to admit that his terrible wound was making things hard for him.

Keen’s old coxswain had been killed aboard their last ship, Al Argonaute.

About the same size, and with just two more guns than the Argonaute, she was undermanned and lacking experienced officers.

Like a hurricane the Argonaute's iron had ripped through her masts and rigging, reducing her to an unmanageable wreck in seconds.

The Argonaute was steering on a converging tack, her yards braced hard round to carry her away from the nearest spit of land.

The Argonaute's sails were coming about, and very slowly she began to stand away, her stern turning towards Trojan's poop like the hinges of a gate.

Very soon these vessels and more beside would endure what Trojan had suffered under Argonaute's guns.

But the Argonaute had dismasted Spite without any challenge or warning.

But you know, as well as I, that we would have been made to strike to the Argonaute if Quinn had been left in charge forrard.

In some ways it would have been better if the Argonaute had not broken off the fight.

Hurt pride, or did he expect to face an eventual court martial at Coutts' instigation over the Argonaute encounter?