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a. (context pharmacology English) Preventing or counteracting psychosis. n. (context pharmacology English) Any of a group of drugs used to treat psychosis.


n. tranquilizer used to treat psychotic conditions when a calming effect is desired [syn: major tranquilizer, major tranquillizer, major tranquilliser, antipsychotic drug, antipsychotic agent, neuroleptic drug, neuroleptic agent, neuroleptic]


Antipsychotics are a class of psychiatric medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. They are increasingly being used in the management of non-psychotic disorders. Antipsychotics are usually effective in relieving symptoms of psychosis. However, their long term use is associated with significant side effects such as involuntary movement disorders and metabolic syndrome.

First-generation antipsychotics, known as typical antipsychotics, were discovered in the 1950s. Most second-generation drugs, known as atypical antipsychotics, have been developed more recently, although the first atypical antipsychotic, clozapine, was discovered in the 1960s and introduced clinically in the 1970s. The terms neuroleptic and major tranquilizer were used for older antipsychotic drugs, but are gradually dropping from use. Both generations of medication tend to block receptors in the brain's dopamine pathways, but atypicals tend to act on serotonin receptors as well. Neuroleptic, which originates from the Greek word νεῦρον neuron ("nerve") and λῆψις lepsis ("seizure" or "fit"), is a reference to neurological side effects.

Usage examples of "antipsychotic".

To control these people, they are given a variety of antipsychotic drugs .

The doctors found the right mix of antipsychotic drugs and his symptoms diminished substantially.

And if she had to make a guess, he was definitely off his antipsychotic medications.

Every Wal-Mart was now issuing almost any antipsychotic medicines of a last ditch effort against this latest card hand dealt by Mr.

It was a simple and courageous move: yesterday I ceased all medication, not only the sedatives but the megavitamins and the antipsychotics.

When his body was free of anticholinergics, the antipsychotics did their job properly.

Delighted, Roy said, "Is Ackblom on any medications, any antipsychotics, that we should continue to give him?

Hearing her words repeated by a man on heavy antipsychotics, Anna realized the revelation sounded exactly like what Lanny would say if he was a paranoid schizophrenic or suffered any of a number of other mental illnesses.