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Affinisine

Affinisine is a monoterpenoid indole alkaloid which can be isolated from plants of the Tabernaemontana genus. Structurally it can be considered a member of the sarpagine alkaloid family and may be synthesized from tryptophan via a Pictet-Spengler reaction. Limited pharmacological testing has indicated that it may be an effective inhibitor of both acetylcholinesterase and butyrylcholinesterase.