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3. Southernmost cross-country U.S. highway

Alternative clues for the word iten

• Cal.-to-Fla. route
• Hwy. through Jacksonville and Phoenix
• Major Fla.-to-Calif. route
• Main lower artery, informally
• Cross-country southern hwy
• Hwy. thru Houston
• Major Calif.-to-Fla. route
• Rte. from Santa Monica to Jacksonville
• Christopher Columbus Transcontinental Hwy.
• Eight-state coast-to-coast rte.