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Answer for the clue "Splenda, mainly ", 9 letters:
sucralose

Word definitions for sucralose in dictionaries

Wikipedia Word definitions in Wikipedia
Sucralose is a non-nutritive sweetener. The majority of ingested sucralose is not broken down by the body, so it is noncaloric. In the European Union , it is also known under the E number E955 . Sucralose is about 320 to 1,000 times sweeter than sucrose ...

Wiktionary Word definitions in Wiktionary
n. A selectively chlorinated sucrose, used as an artificial sweetener under the trade name ''Splenda''.