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Answer for the clue "Lofty circus act locale ", 8 letters:
highwire

Alternative clues for the word highwire

Word definitions for highwire in dictionaries

Wiktionary Word definitions in Wiktionary
alt. An elevated tightrope. n. An elevated tightrope.

Wikipedia Word definitions in Wikipedia
Highwire (Hiw) is an E3 ubiquitin ligase protein associated with neuromuscular junction growth. It is frequently studied in Drosophila melanogaster . Its known orthologs are PAM , RPM-1 , and PHR-1 .

Usage examples of highwire.

She paused for a moment, watching an acrobat making his way gingerly across a highwire suspended far above.

Above were the retracted riggings for aerial and highwire acts, bounce-jousting, and such.

Reassuring herself that she only weighed thirty-five pounds more than the professor, she tripped across the bridge like a highwire walker.