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Answer for the clue "Drug that can cause memory blackouts, in slang ", 6 letters:
roofie

Word definitions for roofie in dictionaries

Wiktionary Word definitions in Wiktionary
n. (context slang often plurale tantum English) The date rape drug flunitrazepam. vb. 1 (context slang transitive English) To put roofies in, to spike with roofies. 2 (context slang transitive English) To cause someone to (usually unknowingly) ingest roofies. ...