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Answer for the clue "Investigation designed to expand knowledge ", 8 letters:
research

Alternative clues for the word research

Word definitions for research in dictionaries

Wikipedia Word definitions in Wikipedia
Research magazine is a U.S. based monthly business-to-business publication. Since 1978, Research magazine has served "National Wirehouses, Regional or Independent Brokerages, Registered Investment Advisories, Bank Brokerages and Financial Planning Firms" ...

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
research \re*search"\, v. t. [Pref. re- + search: cf. OF. recerchier, F. rechercher.] To search or examine with continued care; to seek diligently.

Usage examples of research.

Stillbirths, abortuses, and placentas are in hot demand at the BLI for the dozen or so groups doing hormone research.

Veneziano, then a research fellow at CERN, the European accelerator laboratory in Geneva, Switzerland, had worked on aspects of this problem for a number of years, until one day he came upon a striking revelation.

Into it he had crammed a chair and minuscule table, desk-model accessor, and the accumulated reference materials and data of years of research.

Was Aden really doing what I thought he was doing, essentially establishing me as the goto person for conducting archaeological research in Stone Harbor?

The Institute has been researching high volume advertising since 1954 and is in the business of selling reports that offer statistical data on the most effective media and messages in various industries.

Coral Lorenzen, author of The Great Flying Saucer Hoax and an international director of the Aerial Phenomena Research Organization, immediately followed through on the startling rumors by putting in a call to Terry Clarke of KALG Radio in Alamogordo, nine miles east of Holloman.

Ward himself tried to be more affable, but succeeded only in provoking curiousity with his rambling accounts of chemical research.

Rosicrucian society was the Order of the Gold and Rosy Cross, founded in Germany in 1710 by Sigmund Richter, the primary purpose of which was alchemical research.

That we moved your big soft body with allegedly not enough notice and that east-side school you cried over and that Negro research resource librarian there with the hair out to here that.

All experiments of any kin, upon other adults, whether patients or inmates of public institutions or otherwise, if made without direct ameliorative purpose and the intelligent personal consent of the person who is the MATERIAL for the research.

I know two amphibian research labs in California who are working with live Ranaviruses.

Hundreds of human proteins, from angiotensin to chorionic gonadotropin, were being grown as crystals aboard ISS -- vital pharmaceutical research that could lead to the development of new drugs.

After that, he made a series of aphoristic comments which some have taken to be poems, and other have taken to be seeds for future scientific research.

The machine said: NHLI MASS SPECTRAL SEARCH SYSTEM PROGRAMME: YOUR NAME AND COMPANY PLEASE USER: Fine said Apicultural Research and Development Facility, Ft Detrick, Maryland PROGRAMME: PLEASE TYPE YOUR 3 INITIALS USER: It so happened that George Fine did not have a middle name.

LTP might not be a purely artefactual phenomenon, which occurs only in animals which have been reared in the highly restricted environment of a research laboratory?