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Answer for the clue "Ancient region of Afghanistan ", 7 letters:
bactria

Word definitions for bactria in dictionaries

Wikipedia Word definitions in Wikipedia
Bactria or Bactriana was the name of a historical region in Central Asia . The English name Bactria is derived from the Ancient Greek , a Hellenized version of the Bactrian endonym Bakhlo (βαχλο). Analogous names include the Persian / Pashto باختر Bākhtar ...

Wiktionary Word definitions in Wiktionary
n. The ancient Greek name of the country between the range of the Hindu Kush and the Amu Darya in the Middle East, encompassing parts of northern Afghanistan, eastern Turkmenistan, southern Uzbekistan, Tajikistan and northern Pakistan.

Usage examples of bactria.

He garrisons Bactria to keep the Massagetae at bay, as they are tribes, not a nation.

And according to my invaluable informant Antipater, ten thousand more who survived the first fight further down the Bilechas were rounded up by the Pahlavi Surenas and sent to the frontier of Bactria beyond the Caspian Sea, where they are to be used to keep the Massagetae from raiding.

I have just entered the tent of Hystaspes, satrap of Bactria and Parthia.

Darius indicated the long line of the river that runs from the high mountains east of Bactria down to a complex delta that empties into what is called the Sea of India.

I did one tour of duty in the Ionian cities, where there is no great wealth, and another in Bactria, which is poor.

We were all agreed that the sea route is endless, and that the trail from Bactria to the east is not passable because of the Scythian tribes.

How, I wondered desperately, was I going to kill the satrap of Bactria in his own capital?

Although the recent disturbance in Bactria was mentioned in a somewhat minatory way, no mention was made of the revolt in Egypt.

I suppose the strangeness and the remoteness of Bactria might have had something to do with it.

Masistes and his sons fled to Bactria, where they went into rebellion.

In a matter of months Bactria was subdued, and Masistes and all his family were put to death.

Lopez must find an explanation of the similarity which, as we shall show, exists between the speech of the South American Pacific coast on the one hand, and the speech of Gaul, Ireland, England, Italy, Greece, Bactria, and Hindostan on the other.

And if the Aryans moved at a comparatively recent date into Europe from Bactria, where are the populations that then inhabited Europe--the men of the ages of stone and bronze?

The supreme commander who had borne the Roman eagles to hitherto unexplored shores knew now that he would never embark upon that sea so long in his thoughts: India, Bactria, the whole of that vague East which had intoxicated him from afar, would continue to be for him only names and dreams.

Parthia was a small nation to the northeast of the Caspian Sea, near Bactria, and was important only because it had produced the seven great Pahlavi families, and the Arsacid Parthian kings.