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Answer for the clue "Major bummers ", 9 letters:
comedowns

Word definitions for comedowns in dictionaries

Wiktionary Word definitions in Wiktionary
n. (plural of comedown English)

Usage examples of comedowns.

I’ve seen more comedowns brought about by business associates thinking with {Page 210} their brains in their groins instead of in their heads where they belong.

It wasn't the familiar howling of decapitated brujos that you hear on peyote comedowns, nor the choiring arguments of angels and devils that LSD can provoke.