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Answer for the clue "Salt-N-___ (hip-hop trio whose biggest hit was 1994's "Whatta Man") ", 4 letters:
pepa

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Wikipedia Word definitions in Wikipedia
PEPA is an ampakine drug which acts as an allosteric potentiator of AMPA receptor desensitisation, which is up to 100x more potent than aniracetam in vitro . It produces memory-enhancing effects in rats when administered intravenously.