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Answer for the clue "Losses of sharpness ", 9 letters:
dementias

Word definitions for dementias in dictionaries

Wiktionary Word definitions in Wiktionary
n. (plural of dementia English)

Usage examples of dementias.

And Corrigan liked working there because it offered a respite from the various dementias of the age that he was supposed to want to normalize himself by imitating.

His mind wondered dimly, spinning back to those hillside dementias, and he buried his face in Sakhithe's shoulder, protecting both their heads with his arms.

Gordon said, "so we can eliminate some very serious dementias, which would indicate a complete or near complete loss of intellectual capacity.

Such benefits lie primarily in the treatment of the dementias and other nervous and mental diseases, but doubtless others will accrue as well.

There were the senile dementias, and mad paralysed syphilitics and the nasty idiots, the despair of the world: but they were on the lower floors and in the wings.