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Answer for the clue "Goes off course ", 8 letters:
deviates

Word definitions for deviates in dictionaries

Wiktionary Word definitions in Wiktionary
n. (plural of deviate English) vb. (en-third-person singular of: deviate )

Usage examples of deviates.

His knees clamped on the tail, as he sank his Bowies to the hilt in the genetic deviates back.

Three of these genetic deviates, according to the files, now resided with the Family, had actually joined the Family in its fight with the Doktor, rebelling against their demented creator.

Lysenko had heard other tales about the deviates, about their grotesque appearance and extraordinary abilities, even reports the deviates consumed humans.

States, where an infant whose angle deviates by half a degree from the correct angularity is summarily destroyed at birth.

Zombies closing in, four more of the detestable deviates with a craving for healthy human flesh.