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Answer for the clue ""Giant Brain" in 1946 headlines ", 5 letters:
eniac

Alternative clues for the word eniac

Word definitions for eniac in dictionaries

Douglas Harper's Etymology Dictionary Word definitions in Douglas Harper's Etymology Dictionary
acronym from "electronic numeral integrator and computer," device built 1946 at University of Pennsylvania by John W. Mauchly Jr., J. Presper Eckert Jr., and J.G. Brainerd. It cost $400,000, used 18,000 radio tubes, and was housed in a 30-foot-by-50-foot ...

Usage examples of eniac.

A modern personal computer has far more power and reliability than the first Eniac, and the "hydrocodes" which enable a computer to test and validate a weapon's design are easily duplicated.

All the work on the first hydrogen bomb was done on the first primitive computers - Eniac, I think it was called.