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3. He replaced and was replaced by Leno

Alternative clues for the word obrien

• Redheaded talk show host
• A star of "Seven Days in May"
• 'Tonight Show' host, briefly
• Host Conan ____
• Irish writer Edna
• Leno's successor who didn't succeed
• Rockne portrayer
• Leno's successor-to-be
• Irish author set to eat cheese
• Leno follower