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Answer for the clue "Nintendo avatars ", 4 letters:
miis

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Wikipedia Word definitions in Wikipedia
MIIS (Meditech Interpretive Information System) is a MUMPS -like programming language that was created by A.Neil Pappalardo and Curt W. Marble, on a DEC PDP at Mass General Hospital from 1964 to 1968. MUMPS evolution took two major directions: MUMPS proper ...