Living tissue injuries

Usage examples of lesions.

Thus post-training LPO lesions, which otherwise would be amnestic, should now no longer be.

It is sometimes argued that cuts or lesions in significant parts of the cerebral cortex in humans-as by bilateral prefrontal lobotomy or by an accident-have little effect on behavior.

Patients with lesions of the right temporal lobe or right hemispherectomies are significantly impaired in musical but not in verbal ability- in particular in the recognition and recall of melodies.

Patterson, T A, Gilbert, D B, and Rose, S P R Pre- and posttraining lesions of the intermediate medial hyperstriatum ventrale and passive avoidance learning in the chick.

THE NEOCORTEX Even in fish, lesions of the forebrain destroy the traits of initiative and caution.

The effects of drugs, lesions and other manipulations can readily be tested in this type of equipment by a study of their effect on the speed and directness with which the rat can find the hidden shelf.

The chicks survive the operation and the anaesthesia well, and once they come round, the birds with IMHV or LPO lesions seem quite normal, indistinguishable from sham-operated or normal controls.

Chicks with left-hemisphere IMHV lesions forgot the avoidance, chicks with right hemisphere lesions remembered without difficulty.

To our astonishment, even bilateral lesions made an hour after training did not produce amnesia.

Bilateral LPO lesions, made an hour after training, indeed resulted in amnesia, although unilateral ones, either of right or left LPO, were without effect.

Dave, Terry and I decided to write the definitive paper showing all the new set of lesions and their confirmation of the model.

Davies, D C, Taylor, D A, and Johnson M H The effects of hyperstriatal lesions on one trial passive avoidance learning in the chick.

Again, it is deduced from the finding that many lesions of the brain, generally of the cerebral cortex, have no apparent effect on behavior.

For example, lesions in the right hemisphere of the cerebral cortex may lead to impairments in thought and action, but in the nonverbal realm, which is, by definition, difficult for the patient or the physician to describe.

Memory seems to be localized in specific sites in the brain, and the survival of memories after massive brain lesions must be the result of redundant storage of static memory traces in various locales.