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Answer for the clue "A long time without working is .. .is upsetting in the extreme ", 8 letters:
agonises

Alternative clues for the word agonises

Word definitions for agonises in dictionaries

Wiktionary Word definitions in Wiktionary
vb. (en-third-person singular of: agonise)

Usage examples of agonises.

But the historian groans at anachronisms, agonises over chronologies, and corrects descriptions according to archaeological studies, from city plans to the heights of the people.