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Answer for the clue "Titans of business defeat US Feds, ignoring the odds ", 10 letters:
colossuses

Word definitions for colossuses in dictionaries

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Colossus \Co*los"sus\, n.; pl. L. Colossi , E. Colossuses . A statue of gigantic size. The name was especially applied to certain famous statues in antiquity, as the Colossus of Nero in Rome, the Colossus of Apollo at Rhodes. He doth bestride the narrow ...

Wiktionary Word definitions in Wiktionary
alt. (plural of colossus English) n. (plural of colossus English)

Usage examples of colossuses.

The main branches of these forest colossuses are broader than twelve-lane highways and sturdy enough to support entire cities.