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Answer for the clue "Numbers game played with iPad, rules added ", 9 letters:
epidurals

Word definitions for epidurals in dictionaries

Wiktionary Word definitions in Wiktionary
n. (plural of epidural English)

Usage examples of epidurals.

There were a number of spinal cases, but they would have used spinal HARMFUL INTENT 175 grade Marcaine if Marcaine had been used at all, not the 30 cc variety used for epidurals or regional blocks.