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Answer for the clue "Wrong from the start? ", 12 letters:
original sin

Word definitions for original sin in dictionaries

Wiktionary Word definitions in Wiktionary
n. (context Christianity English) The state of sin, present in each human at birth, that is a direct result of Adam's disobedience to God.

Wikipedia Word definitions in Wikipedia
"Original Sin" is the third episode of the fifth season of the American series The Vampire Diaries , and the series' 92nd episode overall. "Original Sin" was originally aired on October 17, 2013, on The CW . The episode was written by Melinda Hsu Taylor ...

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Original \O*rig"i*nal\, a. [F. original, L. originalis.] Pertaining to the origin or beginning; preceding all others; first in order; primitive; primary; pristine; as, the original state of man; the original laws of a country; the original inventor of a ...

Usage examples of original sin.

The baby is probably the child of incest or rape, so carries the burden of intensified Original Sin.

And behold, there was I received by the scourge of bodily sickness, and I was descending into hell burdened with all the sins that I had committed, both against Thee, myself, and others, many and grievous, over and above that bond of original sin whereby we all die in Adam.