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Answer for the clue "Contents of Asti carafe replaced - with a different wine ", 8 letters:
frascati

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Wikipedia Word definitions in Wikipedia
Frascati is a town and comune in the Metropolitan City of Rome in the Lazio region of central Italy . It is located south-east of Rome , on the Alban Hills close to the ancient city of Tusculum . Frascati is closely associated with science, being the location ...