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Answer for the clue "Made callous by experience ", 12 letters:
casehardened

Word definitions for casehardened in dictionaries

Wiktionary Word definitions in Wiktionary
vb. (en-past of: caseharden )

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Casehardened \Case"hard`ened\, a. Having the surface hardened, as iron tools. Hardened against, or insusceptible to, good influences; rendered callous by persistence in wrongdoing or resistance of good influences; -- said of persons.

Usage examples of casehardened.

The bronze giant, hardly pausing, snapped a casehardened hand to the fellow's spinal nerve center.

On this, the third Sunday of their imprisonment, they were stumbling through the last hour of the day before the lights were extinguished and they were finally permitted to crawl into their casehardened bunks.