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Answer for the clue "Tosspot's sickness ", 10 letters:
crapulence

Alternative clues for the word crapulence

Word definitions for crapulence in dictionaries

Wiktionary Word definitions in Wiktionary
n. 1 sickness or indisposition caused by excessive eating or drinking 2 intemperance; debauchery; excessive indulgence

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Crapulence \Crap"u*lence\ (-?-lens), n. The sickness occasioned by intemperance; surfeit. --Bailey.

WordNet Word definitions in WordNet
n. the act of drinking alcoholic beverages to excess; "drink was his downfall" [syn: drink , drinking , boozing , drunkenness ]

Usage examples of crapulence.

Alcohol crapulence clogs perception, but drug crapulence flays it, and by now the kitchen was a noisome feast for peeled senses.

There's nothing to stop you from associating with my servants if you want to, but I'd prefer not to have the younger ones reduced to a state of crapulence for your purposes.