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Answer for the clue "Caused to go crazy ", 6 letters:
locoed

Word definitions for locoed in dictionaries

Wiktionary Word definitions in Wiktionary
a. (context of livestock English) intoxicated by eating locoweed

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Loco \Lo"co\, v. t. [imp. & p. p. Locoed ; p. pr. & vb. n. Locoing .] To poison with loco; to affect with the loco disease; hence (Colloq.), to render insane or mad. ``The locoed novelist.'' --W. D. Howells.

Usage examples of locoed.

But he looked happy at thet, an' the last words he said, more to himself than to me, I reckon, was, 'I'm some locoed gent, but if she doesn't call me Tom now she's no good!

An' onless you're plumb locoed you'd never risk goin' near Pine or Show Down.

Wal, I put my oar in to-day among the fellers, an' I says: 'What ails you locoed gents?

Here I am, without anything to eat an' no prospects of anything, sitting up on this locoed layout like a sore thumb, an' can't move without hitting myself!