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Answer for the clue "Discomfort ", 7 letters:
misease

Word definitions for misease in dictionaries

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Misease \Mis*ease"\, n. [OE. mesaise, OF. mesaise.] Want of ease; discomfort; misery. [Obs.] --Chaucer.

Wiktionary Word definitions in Wiktionary
n. (label en archaic) suffering, distress.

Usage examples of misease.

And moreover, the misease of hell shall be in default of meat and drink.