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Answer for the clue "Excessive irritability ", 8 letters:
erethism

Alternative clues for the word erethism

Word definitions for erethism in dictionaries

WordNet Word definitions in WordNet
n. an abnormally high degree of irritability or sensitivity or excitability

Wiktionary Word definitions in Wiktionary
n. 1 (context pathology English) Abnormal excitement of a bodily organ or tissue. 2 Any unusual or morbid overexcitement.

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Erethism \Er"e*thism\, n. [Gr. ? irritation, fr. ? to stir, rouse, fr. ? to stir: cf. F. ['e]r['e]thisme.] (Med.) A morbid degree of excitement or irritation in an organ. --Hoblyn.

Wikipedia Word definitions in Wikipedia
Erethism or erethism mercurialis is a neurological disorder which affects the whole central nervous system, as well as a symptom complex derived from mercury poisoning . This is also sometimes known as the mad hatter disease . Historically, this was common ...

Usage examples of erethism.

I did not like Eddu because he suffered from the most overwhelming adolescent sexual erethism I have ever encountered.

That slave, for all his squalid person and sexual erethism and detestable character, was an experienced traveler, and told us or showed us many things of use or interest.