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Answer for the clue "Any of a group of compounds that are inactive precursors of enzymes and require some change (such as the hydrolysis of a fragment that masks an active enzyme) to become active ", 7 letters:
zymogen

Word definitions for zymogen in dictionaries

Wiktionary Word definitions in Wiktionary
n. (context biochemistry English) A proenzyme, or enzyme precursor, which requires a biochemical change (i.e. hydrolysis) to become an active form of the enzyme.

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Zymogen \Zym"o*gen\, n. [Zyme + -gen.] (Physiol. Chem.) A mother substance, or antecedent, of an enzyme or chemical ferment; -- applied to such substances as, not being themselves actual ferments, may by internal changes give rise to a ferment. The pancreas ...

WordNet Word definitions in WordNet
n. any of a group of compounds that are inactive precursors of enzymes and require some change (such as the hydrolysis of a fragment that masks an active enzyme) to become active [syn: proenzyme ]

Wikipedia Word definitions in Wikipedia
A zymogen , also called a proenzyme , is an inactive precursor of an enzyme . A zymogen requires a biochemical change (such as a hydrolysis reaction revealing the active site, or changing the configuration to reveal the active site) for it to become an ...