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Answer for the clue "Abnormal dryness and roughness of the skin ", 10 letters:
xerodermia

Word definitions for xerodermia in dictionaries

Wiktionary Word definitions in Wiktionary
n. (context medicine dated English) xeroderma

WordNet Word definitions in WordNet
n. a mild form of ichthyosis characterized by abnormal dryness and roughness of the skin [syn: xeroderma ]