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Answer for the clue "A painful inflammation of the big toe and foot caused by defects in uric acid metabolism resulting in deposits of the acid and its salts in the blood and joints ", 11 letters:
urarthritis

Word definitions for urarthritis in dictionaries

WordNet Word definitions in WordNet
n. a painful inflammation of the big toe and foot caused by defects in uric acid metabolism resulting in deposits of the acid and its salts in the blood and joints [syn: gout , gouty arthritis ]