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Answer for the clue "A state in which you are unable to function normally and without pain ", 13 letters:
unhealthiness

Word definitions for unhealthiness in dictionaries

Wiktionary Word definitions in Wiktionary
n. The state of being unhealthy.

WordNet Word definitions in WordNet
n. a state in which you are unable to function normally and without pain [syn: ill health , health problem ] [ant: good health ]

Usage examples of unhealthiness.

Do you mean that the unhealthiness of this country is wholly caused by the river?

American directors, including Edsel Ford, realized the political unhealthiness of I.