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Answer for the clue "Chrosomal abnormality in which there is one more than the normal number of chromosomes in a cell ", 7 letters:
trisomy

Word definitions for trisomy in dictionaries

Douglas Harper's Etymology Dictionary Word definitions in Douglas Harper's Etymology Dictionary
1930, from trisome (from tri- + ending from chromosome ) + -y (4).

Wikipedia Word definitions in Wikipedia
A trisomy is a type of polysomy in which there are three instances of a particular chromosome , instead of the normal two. A trisomy is a type of aneuploidy (an abnormal number of chromosomes).

WordNet Word definitions in WordNet
n. chrosomal abnormality in which there is one more than the normal number of chromosomes in a cell

Wiktionary Word definitions in Wiktionary
n. (context cytology English) The presence of three copies, instead of the normal two, of a particular chromosome of an organism.

Usage examples of trisomy.

The second, the minority of cases, was a permanent chromosomal attachment in the mother, a translocation trisomy, a fluke of a fluke that struck mothers of all ages equally.