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Answer for the clue "Characterized by nervousness and quickness to take fright ", 12 letters:
skittishness

Word definitions for skittishness in dictionaries

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Skittish \Skit"tish\, a. [See Skit , v. t.] Easily frightened; timorous; shy; untrustworthy; as, a skittish colt. ``A restiff, skittish jade.'' --L'Estrange. Wanton; restive; freakish; volatile; changeable; fickle. ``Skittish Fortune's ...

Wiktionary Word definitions in Wiktionary
n. The property of being skittish.

WordNet Word definitions in WordNet
n. characterized by nervousness and quickness to take fright [syn: restiveness ]

Usage examples of skittishness.

Key stocks were being dumped across the board as investor uncertainty over the future of the American economy fueled a skittishness that had not completely abated since Dark Friday.

Zap 210, on her part, treated Reith with suspicion, as if begrudging even the intimacy of conversation: a skittishness and prim reserve peculiar in a person who, to the best of his knowledge, had not even a distorted understanding of ordinary sexual processes.

Two more of them were getting acquainted with two magnificent riding horses, who seemed to be getting over their initial skittishness.