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Answer for the clue "Cracks or fissures in the skin (especially around the mouth or anus) ", 8 letters:
rhagades

Word definitions for rhagades in dictionaries

Wiktionary Word definitions in Wiktionary
n. (plural of rhagade English)

Wikipedia Word definitions in Wikipedia
Rhagades is a genus of moths of the Zygaenidae family.

WordNet Word definitions in WordNet
n. cracks or fissures in the skin (especially around the mouth or anus)

Usage examples of rhagades.

Sometimes it presents flaccid bullae like pemphigus foliaceus, and then there are crusts as well as scales, with rhagades on the mouth, anus, etc.