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Answer for the clue "Cracks or fissures in the skin (especially around the mouth or anus) ", 8 letters:
rhagades

Word definitions for rhagades in dictionaries

WordNet Word definitions in WordNet
n. cracks or fissures in the skin (especially around the mouth or anus)

Wikipedia Word definitions in Wikipedia
Rhagades are fissures, cracks, or linear scars in the skin, especially at the angles of the mouth and nose. They tend to form at areas of motion. They can be a result from bacterial infection of skin lesions. They are associated with congenital syphilis ...

Wiktionary Word definitions in Wiktionary
n. (plural of rhagade English)

Usage examples of rhagades.

Sometimes it presents flaccid bullae like pemphigus foliaceus, and then there are crusts as well as scales, with rhagades on the mouth, anus, etc.